Synthetic organotelluride compounds induce the reversal of Pdr5p mediated fluconazole resistance in Saccharomyces cerevisiae

BACKGROUND: Resistance to fluconazole, a commonly used azole antifungal, is a challenge for the treatment of fungal infections. Resistance can be mediated by overexpression of ABC transporters, which promote drug efflux that requires ATP hydrolysis. The Pdr5p ABC transporter of Saccharomyces cerevis...

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Detalles Bibliográficos
Autores principales: Reis de Sá, Leandro Figueira, Toledo, Fabiano Travanca, de Sousa, Bruno Artur, Gonçalves, Augusto César, Tessis, Ana Claudia, Wendler, Edison P, Comasseto, João V, Dos Santos, Alcindo A, Ferreira-Pereira, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222501/
https://www.ncbi.nlm.nih.gov/pubmed/25062749
http://dx.doi.org/10.1186/s12866-014-0201-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222501/
https://www.ncbi.nlm.nih.gov/pubmed/25062749
http://dx.doi.org/10.1186/s12866-014-0201-y

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