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Modified Bleomycin Disaccharides Exhibiting Improved Tumor Cell Targeting
[Image: see text] The bleomycins (BLMs) are a family of antitumor antibiotics used clinically for anticancer chemotherapy. Their antitumor selectivity derives at least in part from their ability to target tumor cells, a property that resides in the carbohydrate moiety of the antitumor agent. In earl...
Autores principales: | Madathil, Manikandadas M., Bhattacharya, Chandrabali, Yu, Zhiqiang, Paul, Rakesh, Rishel, Michael J., Hecht, Sidney M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222530/ https://www.ncbi.nlm.nih.gov/pubmed/25272367 http://dx.doi.org/10.1021/bi501102z |
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