THOC5, a member of the mRNA export complex, contributes to processing of a subset of wingless/integrated (Wnt) target mRNAs and integrity of the gut epithelial barrier

BACKGROUND: THO (Suppressors of the transcriptional defects of hpr1 delta by overexpression) complex 5 (THOC5), an mRNA export protein, is involved in the expression of only 1% of all genes. Using an interferon inducible knockout mouse system, we have previously shown that THOC5 is an essential elem...

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Detalles Bibliográficos
Autores principales: Saran, Shashank, Tran, Doan DH, Klebba-Färber, Sabine, Moran-Losada, Patricia, Wiehlmann, Lutz, Koch, Alexandra, Chopra, Himpriya, Pabst, Oliver, Hoffmann, Andrea, Klopfleisch, Robert, Tamura, Teruko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222586/
https://www.ncbi.nlm.nih.gov/pubmed/24267292
http://dx.doi.org/10.1186/1471-2121-14-51

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