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Hybridizing Ultraviolet Photodissociation with Electron Transfer Dissociation for Intact Protein Characterization
[Image: see text] We report a hybrid fragmentation method involving electron transfer dissociation (ETD) combined with ultraviolet photodissociation (UVPD) at 193 nm for analysis of intact proteins in an Orbitrap mass spectrometer. Integrating the two fragmentation methods resulted in an increase in...
Autores principales: | Cannon, Joe R., Holden, Dustin D., Brodbelt, Jennifer S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American
Chemical
Society
2014
|
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222623/ https://www.ncbi.nlm.nih.gov/pubmed/25270663 http://dx.doi.org/10.1021/ac5036082 |
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