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Hybridizing Ultraviolet Photodissociation with Electron Transfer Dissociation for Intact Protein Characterization

[Image: see text] We report a hybrid fragmentation method involving electron transfer dissociation (ETD) combined with ultraviolet photodissociation (UVPD) at 193 nm for analysis of intact proteins in an Orbitrap mass spectrometer. Integrating the two fragmentation methods resulted in an increase in...

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Detalles Bibliográficos
Autores principales: Cannon, Joe R., Holden, Dustin D., Brodbelt, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222623/
https://www.ncbi.nlm.nih.gov/pubmed/25270663
http://dx.doi.org/10.1021/ac5036082

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