Curcumin could reduce the monomer of TTR with Tyr114Cys mutation via autophagy in cell model of familial amyloid polyneuropathy

Transthyretin (TTR) familial amyloid polyneuropathy (FAP) is an autosomal dominant inherited neurodegenerative disorder caused by various mutations in the transthyretin gene. We aimed to identify the mechanisms underlying TTR FAP with Tyr114Cys (Y114C) mutation. Our study showed that TTR Y114C mutat...

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Detalles Bibliográficos
Autores principales: Li, Hui, Zhang, Yu, Cao, Li, Xiong, Ran, Zhang, Bei, Wu, Li, Zhao, Zongbo, Chen, Sheng-Di
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222630/
https://www.ncbi.nlm.nih.gov/pubmed/25382970
http://dx.doi.org/10.2147/DDDT.S70866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222630/
https://www.ncbi.nlm.nih.gov/pubmed/25382970
http://dx.doi.org/10.2147/DDDT.S70866

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