Myelin Basic Protein and a Multiple Sclerosis-related MBP-peptide Bind to Oligonucleotides

Aptamer ligands for myelin basic protein (MBP) were obtained using the systematic evolution of ligand by exponential enrichment (SELEX) method. Two clones were isolated from a pool of oligonucleotides and tested for MBP targeting. Using purified MBP, we demonstrated the binding activity of the aptam...

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Detalles Bibliográficos
Autores principales: Rozenblum, Guido Tomás, Kaufman, Tomás, Vitullo, Alfredo Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222649/
https://www.ncbi.nlm.nih.gov/pubmed/25202925
http://dx.doi.org/10.1038/mtna.2014.43

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222649/
https://www.ncbi.nlm.nih.gov/pubmed/25202925
http://dx.doi.org/10.1038/mtna.2014.43

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