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The tumor marker Fascin is induced by the Epstein-Barr virus-encoded oncoprotein LMP1 via NF-κB in lymphocytes and contributes to their invasive migration
BACKGROUND: The actin-bundling protein Fascin (FSCN1) is a tumor marker that is highly expressed in numerous types of cancer including lymphomas and is important for migration and metastasis of tumor cells. Fascin has also been detected in B lymphocytes that are freshly-infected with Epstein-Barr vi...
Autores principales: | Mohr, Caroline F, Kalmer, Martina, Gross, Christine, Mann, Melanie C, Sterz, Kai R, Kieser, Arnd, Fleckenstein, Bernhard, Kress, Andrea K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222691/ https://www.ncbi.nlm.nih.gov/pubmed/25105941 http://dx.doi.org/10.1186/s12964-014-0046-x |
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