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Impaired noradrenaline homeostasis in rats with painful diabetic neuropathy as a target of duloxetine analgesia
BACKGROUND: Painful diabetic neuropathy (PDN) is a serious complication of diabetes mellitus that affects a large number of patients in many countries. The molecular mechanisms underlying the exaggerated nociception in PDN have not been established. Recently, duloxetine (DLX), a serotonin and noradr...
Autores principales: | Kinoshita, Jun, Takahashi, Yukari, Watabe, Ayako M, Utsunomiya, Kazunori, Kato, Fusao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222693/ https://www.ncbi.nlm.nih.gov/pubmed/24279796 http://dx.doi.org/10.1186/1744-8069-9-59 |
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