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ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing

Transposon-insertion sequencing (TIS) is a powerful approach for deciphering genetic requirements for bacterial growth in different conditions, as it enables simultaneous genome-wide analysis of the fitness of thousands of mutants. However, current methods for comparative analysis of TIS data do not...

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Detalles Bibliográficos
Autores principales: Pritchard, Justin R., Chao, Michael C., Abel, Sören, Davis, Brigid M., Baranowski, Catherine, Zhang, Yanjia J., Rubin, Eric J., Waldor, Matthew K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222735/
https://www.ncbi.nlm.nih.gov/pubmed/25375795
http://dx.doi.org/10.1371/journal.pgen.1004782