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ARTIST: High-Resolution Genome-Wide Assessment of Fitness Using Transposon-Insertion Sequencing
Transposon-insertion sequencing (TIS) is a powerful approach for deciphering genetic requirements for bacterial growth in different conditions, as it enables simultaneous genome-wide analysis of the fitness of thousands of mutants. However, current methods for comparative analysis of TIS data do not...
Autores principales: | Pritchard, Justin R., Chao, Michael C., Abel, Sören, Davis, Brigid M., Baranowski, Catherine, Zhang, Yanjia J., Rubin, Eric J., Waldor, Matthew K. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222735/ https://www.ncbi.nlm.nih.gov/pubmed/25375795 http://dx.doi.org/10.1371/journal.pgen.1004782 |
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