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24-Hour Rhythms of DNA Methylation and Their Relation with Rhythms of RNA Expression in the Human Dorsolateral Prefrontal Cortex
Circadian rhythms modulate the biology of many human tissues, including brain tissues, and are driven by a near 24-hour transcriptional feedback loop. These rhythms are paralleled by 24-hour rhythms of large portions of the transcriptome. The role of dynamic DNA methylation in influencing these rhyt...
Autores principales: | Lim, Andrew S. P., Srivastava, Gyan P., Yu, Lei, Chibnik, Lori B., Xu, Jishu, Buchman, Aron S., Schneider, Julie A., Myers, Amanda J., Bennett, David A., De Jager, Philip L. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222754/ https://www.ncbi.nlm.nih.gov/pubmed/25375876 http://dx.doi.org/10.1371/journal.pgen.1004792 |
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