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Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese

BACKGROUND: Although over-the-counter traditional Chinese herbal medicine (COTC) is commonly used to treat everyday illness in many parts of the world, no population-based study has been done to examine the prevalence and factors associated with COTC-related adverse events. METHODS: A cross-sectiona...

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Autores principales: Kim, Jean H, Kwong, Elizabeth MS, Chung, Vincent CH, Lee, John CO, Wong, Terry, Goggins, William B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222756/
https://www.ncbi.nlm.nih.gov/pubmed/24279604
http://dx.doi.org/10.1186/1472-6882-13-336
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author Kim, Jean H
Kwong, Elizabeth MS
Chung, Vincent CH
Lee, John CO
Wong, Terry
Goggins, William B
author_facet Kim, Jean H
Kwong, Elizabeth MS
Chung, Vincent CH
Lee, John CO
Wong, Terry
Goggins, William B
author_sort Kim, Jean H
collection PubMed
description BACKGROUND: Although over-the-counter traditional Chinese herbal medicine (COTC) is commonly used to treat everyday illness in many parts of the world, no population-based study has been done to examine the prevalence and factors associated with COTC-related adverse events. METHODS: A cross-sectional telephone survey was conducted among Hong Kong Chinese adults in 2011 (n = 1100) with informed verbal consent. Stepwise logistic regression of demographic, attitudinal and behavioral variables was used to determine factors associated with past-year adverse events. RESULTS: Of study respondents, 71.7% (789/1100) reported past-year COTC use and 2.3% (25/1100) reported at least one COTC-related adverse event in the past year. Of the 27 adverse events cases reported among COTC users, the most common were allergic reactions (n = 11) dizziness (n = 5), and gastro-intestinal problems (n = 4). Pills/capsules were the dosage form that caused the highest proportion of adverse events (n = 10), followed by plasters (n = 7), creams/ointments (n = 5), and ingestible powders (n = 2). Although COTC users reporting adverse events were more likely to report greater practices to avoid adverse events (OR = 6.47; 95% CI: 1.38-30.3); they were also more likely to possess lower education levels (OR = 9.64, 95% CI: 2.20-42.3) and to have received COTC information from non-reliable, mass-media information sources such as magazines (OR = 3.32; 95% CI: 1.01-8.50) or television (OR = 2.93; 95% CI: 1.03-10.7). Package labels were also felt to be unclear by 42.9% of COTC users. A large proportion of COTC users demonstrated low levels of COTC-related knowledge, while the main impediment to greater information-seeking was the belief that reliable COTC information is not obtainable from Western health professionals. CONCLUSIONS: Despite global movements toward more stringent complementary medicine regulation, the limited accessibility of reliable information and widespread misperceptions among consumers present major challenges for the safe use of complementary medicine.
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spelling pubmed-42227562014-11-07 Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese Kim, Jean H Kwong, Elizabeth MS Chung, Vincent CH Lee, John CO Wong, Terry Goggins, William B BMC Complement Altern Med Research Article BACKGROUND: Although over-the-counter traditional Chinese herbal medicine (COTC) is commonly used to treat everyday illness in many parts of the world, no population-based study has been done to examine the prevalence and factors associated with COTC-related adverse events. METHODS: A cross-sectional telephone survey was conducted among Hong Kong Chinese adults in 2011 (n = 1100) with informed verbal consent. Stepwise logistic regression of demographic, attitudinal and behavioral variables was used to determine factors associated with past-year adverse events. RESULTS: Of study respondents, 71.7% (789/1100) reported past-year COTC use and 2.3% (25/1100) reported at least one COTC-related adverse event in the past year. Of the 27 adverse events cases reported among COTC users, the most common were allergic reactions (n = 11) dizziness (n = 5), and gastro-intestinal problems (n = 4). Pills/capsules were the dosage form that caused the highest proportion of adverse events (n = 10), followed by plasters (n = 7), creams/ointments (n = 5), and ingestible powders (n = 2). Although COTC users reporting adverse events were more likely to report greater practices to avoid adverse events (OR = 6.47; 95% CI: 1.38-30.3); they were also more likely to possess lower education levels (OR = 9.64, 95% CI: 2.20-42.3) and to have received COTC information from non-reliable, mass-media information sources such as magazines (OR = 3.32; 95% CI: 1.01-8.50) or television (OR = 2.93; 95% CI: 1.03-10.7). Package labels were also felt to be unclear by 42.9% of COTC users. A large proportion of COTC users demonstrated low levels of COTC-related knowledge, while the main impediment to greater information-seeking was the belief that reliable COTC information is not obtainable from Western health professionals. CONCLUSIONS: Despite global movements toward more stringent complementary medicine regulation, the limited accessibility of reliable information and widespread misperceptions among consumers present major challenges for the safe use of complementary medicine. BioMed Central 2013-11-27 /pmc/articles/PMC4222756/ /pubmed/24279604 http://dx.doi.org/10.1186/1472-6882-13-336 Text en Copyright © 2013 Kim et al.; licensee BioMed Central Ltd. http://creativecommons.org/licenses/by/2.0 This is an open access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Kim, Jean H
Kwong, Elizabeth MS
Chung, Vincent CH
Lee, John CO
Wong, Terry
Goggins, William B
Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese
title Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese
title_full Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese
title_fullStr Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese
title_full_unstemmed Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese
title_short Acute adverse events from over-the-counter Chinese herbal medicines: a population-based survey of Hong Kong Chinese
title_sort acute adverse events from over-the-counter chinese herbal medicines: a population-based survey of hong kong chinese
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222756/
https://www.ncbi.nlm.nih.gov/pubmed/24279604
http://dx.doi.org/10.1186/1472-6882-13-336
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