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Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging
BACKGROUND: Complex species-specific, developmental- and tissue-dependent mechanisms regulate alternative splicing of tau, thereby diversifying tau protein synthesis. The functional role of alternative splicing of tau e.g. exon 10 has never been examined in vivo, although genetic studies suggest tha...
Autores principales: | Gumucio, Astrid, Lannfelt, Lars, Nilsson, Lars NG |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222861/ https://www.ncbi.nlm.nih.gov/pubmed/24261309 http://dx.doi.org/10.1186/1471-2202-14-148 |
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