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Lack of exon 10 in the murine tau gene results in mild sensorimotor defects with aging

BACKGROUND: Complex species-specific, developmental- and tissue-dependent mechanisms regulate alternative splicing of tau, thereby diversifying tau protein synthesis. The functional role of alternative splicing of tau e.g. exon 10 has never been examined in vivo, although genetic studies suggest tha...

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Detalles Bibliográficos
Autores principales: Gumucio, Astrid, Lannfelt, Lars, Nilsson, Lars NG
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222861/
https://www.ncbi.nlm.nih.gov/pubmed/24261309
http://dx.doi.org/10.1186/1471-2202-14-148

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