Stage-Specific Binding Profiles of Cohesin in Resting and Activated B Lymphocytes Suggest a Role for Cohesin in Immunoglobulin Class Switching and Maturation

The immunoglobulin heavy chain locus (Igh) features higher-order chromosomal interactions to facilitate stage-specific assembly of the Ig molecule. Cohesin, a ring-like protein complex required for sister chromatid cohesion, shapes chromosome architecture and chromatin interactions important for tra...

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Detalles Bibliográficos
Autores principales: Günal-Sadık, Gamze, Paszkowski-Rogacz, Maciej, Singaravelu, Kalaimathy, Beyer, Andreas, Buchholz, Frank, Jessberger, Rolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4222939/
https://www.ncbi.nlm.nih.gov/pubmed/25375358
http://dx.doi.org/10.1371/journal.pone.0111748

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