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IL-37 Inhibits Inflammasome Activation and Disease Severity in Murine Aspergillosis

Since IL-37 transgenic mice possesses broad anti-inflammatory properties, we assessed whether recombinant IL-37 affects inflammation in a murine model of invasive pulmonary aspergillosis. Recombinant human IL-37 was injected intraperitoneally into mice prior to infection and the effects on lung infl...

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Detalles Bibliográficos
Autores principales:	Moretti, Silvia, Bozza, Silvia, Oikonomou, Vasilis, Renga, Giorgia, Casagrande, Andrea, Iannitti, Rossana G., Puccetti, Matteo, Garlanda, Cecilia, Kim, Soohyun, Li, Suzhao, van de Veerdonk, Frank L., Dinarello, Charles A., Romani, Luigina
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223056/ https://www.ncbi.nlm.nih.gov/pubmed/25375146 http://dx.doi.org/10.1371/journal.ppat.1004462

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