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Silencing by H-NS Potentiated the Evolution of Salmonella
The bacterial H-NS protein silences expression from sequences with higher AT-content than the host genome and is believed to buffer the fitness consequences associated with foreign gene acquisition. Loss of H-NS results in severe growth defects in Salmonella, but the underlying reasons were unclear....
Autores principales: | Ali, Sabrina S., Soo, Jeremy, Rao, Chitong, Leung, Andrea S., Ngai, David Hon-Man, Ensminger, Alexander W., Navarre, William Wiley |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223078/ https://www.ncbi.nlm.nih.gov/pubmed/25375226 http://dx.doi.org/10.1371/journal.ppat.1004500 |
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