Evolution of extensively drug-resistant Mycobacterium tuberculosis from a susceptible ancestor in a single patient

BACKGROUND: Mycobacterium tuberculosis is characterized by a low mutation rate and a lack of genetic recombination. Yet, the rise of extensively resistant strains paints a picture of a microbe with an impressive adaptive potential. Here we describe the first documented case of extensively drug-resis...

Descripción completa

Detalles Bibliográficos
Autores principales: Eldholm, Vegard, Norheim, Gunnstein, von der Lippe, Bent, Kinander, Wibeke, Dahle, Ulf R, Caugant, Dominique A, Mannsåker, Turid, Mengshoel, Anne Torunn, Dyrhol-Riise, Anne Ma, Balloux, Francois
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223161/
https://www.ncbi.nlm.nih.gov/pubmed/25418686
http://dx.doi.org/10.1186/s13059-014-0490-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223161/
https://www.ncbi.nlm.nih.gov/pubmed/25418686
http://dx.doi.org/10.1186/s13059-014-0490-3

Ejemplares similares