Auxin-induced Rapid Degradation of Inhibitor of Caspase-activated DNase (ICAD) Induces Apoptotic DNA Fragmentation, Caspase Activation, and Cell Death: A CELL SUICIDE MODULE

Caspase-activated DNase (CAD) is a major apoptotic nuclease, responsible for DNA fragmentation and chromatin condensation during apoptosis. CAD is normally activated in apoptosis as a result of caspase cleavage of its inhibitory chaperone ICAD. Other aspects of CAD regulation are poorly understood....

Descripción completa

Detalles Bibliográficos
Autores principales: Samejima, Kumiko, Ogawa, Hiromi, Ageichik, Alexander V., Peterson, Kevin L., Kaufmann, Scott H., Kanemaki, Masato T., Earnshaw, William C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2014
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223357/
https://www.ncbi.nlm.nih.gov/pubmed/25248749
http://dx.doi.org/10.1074/jbc.M114.583542

Ejemplares similares

Ejemplares similares