The mutation profile of JAK2 and CALR in Chinese Han patients with Philadelphia chromosome-negative myeloproliferative neoplasms

Mutations in JAK2, MPL and CALR are highly relevant to the Philadelphia chromosome (Ph)-negative myeloproliferative neoplasms (MPNs). We performed high resolution melting analysis and Sanger sequencing together with T-A cloning to elucidate the unique mutation profile of these genes, in Chinese pati...

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Detalles Bibliográficos
Autores principales: Wu, Zhiyuan, Zhang, Xinju, Xu, Xiao, Chen, Yuming, Hu, Tingting, Kang, Zhihua, Li, Shibao, Wang, Hua, Liu, Weiwei, Ma, Xiaochao, Guan, Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223390/
https://www.ncbi.nlm.nih.gov/pubmed/25023898
http://dx.doi.org/10.1186/s13045-014-0048-6

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