HMGB1 mediates splenomegaly and expansion of splenic CD11b+ Ly-6C(high) inflammatory monocytes in murine sepsis survivors

BACKGROUND: More than 500,000 hospitalized patients survive severe sepsis annually in the USA. Recent epidemiological evidence, however, demonstrated that these survivors have significant morbidity and mortality, with 3-year fatality rates higher than 70%. To investigate the mechanisms underlying pe...

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Detalles Bibliográficos
Autores principales: Valdés-Ferrer, S I, Rosas-Ballina, M, Olofsson, P S, Lu, B, Dancho, M E, Ochani, M, Li, J H, Scheinerman, J A, Katz, D A, Levine, Y A, Hudson, L K, Yang, H, Pavlov, V A, Roth, J, Blanc, L, Antoine, D J, Chavan, S S, Andersson, U, Diamond, B, Tracey, K J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2013
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223507/
https://www.ncbi.nlm.nih.gov/pubmed/23808943
http://dx.doi.org/10.1111/joim.12104

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