Potential use of human adipose mesenchymal stromal cells for intervertebral disc regeneration: a preliminary study on biglycan-deficient murine model of chronic disc degeneration

INTRODUCTION: Biglycan is an important proteoglycan of the extracellular matrix of intervertebral disc (IVD), and its decrease with aging has been correlated with IVD degeneration. Biglycan deficient (Bgn(−/0)) mice lack this protein and undergo spontaneous IVD degeneration with aging, thus represen...

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Detalles Bibliográficos
Autores principales: Marfia, Giovanni, Campanella, Rolando, Navone, Stefania Elena, Zucca, Ileana, Scotti, Alessandro, Figini, Matteo, Di Vito, Clara, Alessandri, Giulio, Riboni, Laura, Parati, Eugenio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223513/
https://www.ncbi.nlm.nih.gov/pubmed/25293819
http://dx.doi.org/10.1186/s13075-014-0457-5

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