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Ubiquitin-conjugating enzyme complex Uev1A-Ubc13 promotes breast cancer metastasis through nuclear factor-кB mediated matrix metalloproteinase-1 gene regulation

INTRODUCTION: UEV1A encodes a ubiquitin-conjugating enzyme variant (Ubc13), which is required for Ubc13-catalyzed Lys63-linked polyubiquitination of target proteins and nuclear factor κB (NF-кB) activation. Previous reports have correlated the level of UEV1A expression with tumorigenesis; however, t...

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Detalles Bibliográficos
Autores principales:	Wu, Zhaojia, Shen, Siqi, Zhang, Zhiling, Zhang, Weiwei, Xiao, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223564/ https://www.ncbi.nlm.nih.gov/pubmed/25022892 http://dx.doi.org/10.1186/bcr3692

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