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Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues
The BMP ligand Dpp, operates as a long range morphogen to control many important functions during Drosophila development from tissue patterning to growth. The BMP signal is transduced intracellularly via C-terminal phosphorylation of the BMP transcription factor Mad, which forms an activity gradient...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223678/ https://www.ncbi.nlm.nih.gov/pubmed/25377173 http://dx.doi.org/10.1038/srep06927 |