Mad linker phosphorylations control the intensity and range of the BMP-activity gradient in developing Drosophila tissues

The BMP ligand Dpp, operates as a long range morphogen to control many important functions during Drosophila development from tissue patterning to growth. The BMP signal is transduced intracellularly via C-terminal phosphorylation of the BMP transcription factor Mad, which forms an activity gradient...

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Detalles Bibliográficos
Autores principales: Aleman, Abigail, Rios, Marlyn, Juarez, Matthew, Lee, Daniel, Chen, Annan, Eivers, Edward
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223678/
https://www.ncbi.nlm.nih.gov/pubmed/25377173
http://dx.doi.org/10.1038/srep06927

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