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Naproxen affects osteogenesis of human mesenchymal stem cells via regulation of Indian hedgehog signaling molecules
INTRODUCTION: We previously showed that type X collagen, a marker of late stage chondrocyte hypertrophy (associated with endochondral ossification), is constitutively expressed by mesenchymal stem cells (MSCs) from osteoarthritis patients and this may be related to Naproxen (Npx), a nonsteroidal ant...
Autores principales: | Salem, Omar, Wang, Hong Tian, Alaseem, Abdulrahman M, Ciobanu, Ovidiu, Hadjab, Insaf, Gawri, Rahul, Antoniou, John, Mwale, Fackson |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223691/ https://www.ncbi.nlm.nih.gov/pubmed/25034046 http://dx.doi.org/10.1186/ar4614 |
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