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Human iPSC Neurons Display Activity-Dependent Neurotransmitter Secretion: Aberrant Catecholamine Levels in Schizophrenia Neurons
This study investigated human-induced pluripotent stem cell (hiPSC) -derived neurons for their ability to secrete neurotransmitters in an activity-dependent manner, the fundamental property required for chemical neurotransmission. Cultured hiPSC neurons showed KCl stimulation of activity-dependent s...
Autores principales: | Hook, Vivian, Brennand, Kristen J., Kim, Yongsung, Toneff, Thomas, Funkelstein, Lydiane, Lee, Kelly C., Ziegler, Michael, Gage, Fred H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223699/ https://www.ncbi.nlm.nih.gov/pubmed/25358781 http://dx.doi.org/10.1016/j.stemcr.2014.08.001 |
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