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Evaluation of the transporter-mediated herb-drug interaction potential of DA-9801, a standardized dioscorea extract for diabetic neuropathy, in human in vitro and rat in vivo

BACKGROUND: Drug transporters play important roles in the absorption, distribution, and elimination of drugs and thereby, modulate drug efficacy and toxicity. With a growing use of poly pharmacy, concurrent administration of herbal extracts that modulate transporter activities with drugs can cause s...

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Detalles Bibliográficos
Autores principales: Song, Im-Sook, Kong, Tae Yeon, Jeong, Hyeon-Uk, Kim, Eun Nam, Kwon, Soon-Sang, Kang, Hee Eun, Choi, Sang-Zin, Son, Miwon, Lee, Hye Suk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223725/
https://www.ncbi.nlm.nih.gov/pubmed/25034211
http://dx.doi.org/10.1186/1472-6882-14-251