The size of the primary tumor and age at initial diagnosis are independent predictors of the metastatic behavior and survival of patients with SDHB-related pheochromocytoma and paraganglioma: a retrospective cohort study

BACKGROUND: Succinate dehydrogenase subunit B (SDHB) mutations are associated with aggressive pheochromocytoma (PHEO)/paraganglioma (PGL) behavior, often resulting in metastatic disease and fatal outcomes. These tumors are often larger, extra-adrenal, and contain lower catecholamine concentrations t...

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Detalles Bibliográficos
Autores principales: Schovanek, Jan, Martucci, Victoria, Wesley, Robert, Fojo, Tito, del Rivero, Jaydira, Huynh, Thanh, Adams, Karen, Kebebew, Electron, Frysak, Zdenek, Stratakis, Constantine A, Pacak, Karel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223758/
https://www.ncbi.nlm.nih.gov/pubmed/25048685
http://dx.doi.org/10.1186/1471-2407-14-523

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