Drp1 inhibition attenuates neurotoxicity and dopamine release deficits in vivo

Mitochondrial dysfunction has been reported in both familial and sporadic Parkinson’s disease (PD). However, effective therapy targeting this pathway is currently inadequate. Recent studies suggest that manipulating the processes of mitochondrial fission and fusion has considerable potential for tre...

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Detalles Bibliográficos
Autores principales: Rappold, Phillip M., Cui, Mei, Grima, Jonathan C., Fan, Rebecca Z., de Mesy-Bentley, Karen L., Chen, Linan, Zhuang, Xiaoxi, Bowers, William J., Tieu, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223875/
https://www.ncbi.nlm.nih.gov/pubmed/25370169
http://dx.doi.org/10.1038/ncomms6244

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