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Inhaled dsRNA and rhinovirus evoke neutrophilic exacerbation and lung expression of thymic stromal lymphopoietin in allergic mice with established experimental asthma

BACKGROUND: Rhinovirus infection or dsRNA stimulation increased thymic stromal lymphopoietin (TSLP), an upstream pro-allergic cytokine, in asthmatic bronchial epithelial cells. We hypothesized that dsRNA challenges superimposed on established experimental allergic asthma constitute a useful exacerba...

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Detalles Bibliográficos
Autores principales: Mahmutovic-Persson, I, Akbarshahi, H, Bartlett, N W, Glanville, N, Johnston, S L, Brandelius, A, Uller, L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223976/
https://www.ncbi.nlm.nih.gov/pubmed/24283976
http://dx.doi.org/10.1111/all.12329