SGLT2 inhibitor lowers serum uric acid through alteration of uric acid transport activity in renal tubule by increased glycosuria

Sodium glucose cotransporter 2 (SGLT2) inhibitors have been reported to lower the serum uric acid (SUA) level. To elucidate the mechanism responsible for this reduction, SUA and the urinary excretion rate of uric acid (UE(UA)) were analysed after the oral administration of luseogliflozin, a SGLT2 in...

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Detalles Bibliográficos
Autores principales: Chino, Yukihiro, Samukawa, Yoshishige, Sakai, Soichi, Nakai, Yasuhiro, Yamaguchi, Jun-ichi, Nakanishi, Takeo, Tamai, Ikumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4223977/
https://www.ncbi.nlm.nih.gov/pubmed/25044127
http://dx.doi.org/10.1002/bdd.1909

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