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Functional analysis of tanshinone IIA that blocks the redox function of human apurinic/apyrimidinic endonuclease 1/redox factor-1

Apurinic/apyrimidinic endonuclease 1/redox factor-1 (APE1/Ref-1) is a multifunctional protein possessing both DNA repair and redox regulatory activities. It has been shown that blocking redox function leads to genotoxic, antiangiogenic, cytostatic, and proapoptotic effects in cells. Therefore, the s...

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Detalles Bibliográficos
Autores principales:	Sui, Jiangdong, Li, Mengxia, Qian, Chengyuan, Wang, Shufeng, Cheng, Yi, Chen, Benjamin PC, Wang, Dong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2014
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224025/ https://www.ncbi.nlm.nih.gov/pubmed/25395832 http://dx.doi.org/10.2147/DDDT.S71124

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