Cargando…

PolyprOnline: polyproline helix II and secondary structure assignment database

The polyproline helix type II (PPII) is a regular protein secondary structure with remarkable features. Many studies have highlighted different crucial biological roles supported by this local conformation, e.g. in the interactions between biological macromolecules. Although PPII is less frequently...

Descripción completa

Detalles Bibliográficos
Autores principales: Chebrek, Romain, Leonard, Sylvain, de Brevern, Alexandre G., Gelly, Jean-Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224144/
https://www.ncbi.nlm.nih.gov/pubmed/25380779
http://dx.doi.org/10.1093/database/bau102
_version_ 1782343314818727936
author Chebrek, Romain
Leonard, Sylvain
de Brevern, Alexandre G.
Gelly, Jean-Christophe
author_facet Chebrek, Romain
Leonard, Sylvain
de Brevern, Alexandre G.
Gelly, Jean-Christophe
author_sort Chebrek, Romain
collection PubMed
description The polyproline helix type II (PPII) is a regular protein secondary structure with remarkable features. Many studies have highlighted different crucial biological roles supported by this local conformation, e.g. in the interactions between biological macromolecules. Although PPII is less frequently present than regular secondary structures such as canonical alpha helices and beta strands, it corresponds to 3–10% of residues. Up to now, PPII is not assigned by most popular assignment tools, and therefore, remains insufficiently studied. PolyprOnline database is, therefore, dedicated to PPII structure assignment and analysis to facilitate the study of PPII structure and functional roles. This database is freely accessible from www.dsimb.inserm.fr/dsimb_tools/polyproline.
format Online
Article
Text
id pubmed-4224144
institution National Center for Biotechnology Information
language English
publishDate 2014
publisher Oxford University Press
record_format MEDLINE/PubMed
spelling pubmed-42241442014-11-10 PolyprOnline: polyproline helix II and secondary structure assignment database Chebrek, Romain Leonard, Sylvain de Brevern, Alexandre G. Gelly, Jean-Christophe Database (Oxford) Original Article The polyproline helix type II (PPII) is a regular protein secondary structure with remarkable features. Many studies have highlighted different crucial biological roles supported by this local conformation, e.g. in the interactions between biological macromolecules. Although PPII is less frequently present than regular secondary structures such as canonical alpha helices and beta strands, it corresponds to 3–10% of residues. Up to now, PPII is not assigned by most popular assignment tools, and therefore, remains insufficiently studied. PolyprOnline database is, therefore, dedicated to PPII structure assignment and analysis to facilitate the study of PPII structure and functional roles. This database is freely accessible from www.dsimb.inserm.fr/dsimb_tools/polyproline. Oxford University Press 2014-11-06 /pmc/articles/PMC4224144/ /pubmed/25380779 http://dx.doi.org/10.1093/database/bau102 Text en © The Author(s) 2014. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Chebrek, Romain
Leonard, Sylvain
de Brevern, Alexandre G.
Gelly, Jean-Christophe
PolyprOnline: polyproline helix II and secondary structure assignment database
title PolyprOnline: polyproline helix II and secondary structure assignment database
title_full PolyprOnline: polyproline helix II and secondary structure assignment database
title_fullStr PolyprOnline: polyproline helix II and secondary structure assignment database
title_full_unstemmed PolyprOnline: polyproline helix II and secondary structure assignment database
title_short PolyprOnline: polyproline helix II and secondary structure assignment database
title_sort polypronline: polyproline helix ii and secondary structure assignment database
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224144/
https://www.ncbi.nlm.nih.gov/pubmed/25380779
http://dx.doi.org/10.1093/database/bau102
work_keys_str_mv AT chebrekromain polypronlinepolyprolinehelixiiandsecondarystructureassignmentdatabase
AT leonardsylvain polypronlinepolyprolinehelixiiandsecondarystructureassignmentdatabase
AT debrevernalexandreg polypronlinepolyprolinehelixiiandsecondarystructureassignmentdatabase
AT gellyjeanchristophe polypronlinepolyprolinehelixiiandsecondarystructureassignmentdatabase