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PolyprOnline: polyproline helix II and secondary structure assignment database
The polyproline helix type II (PPII) is a regular protein secondary structure with remarkable features. Many studies have highlighted different crucial biological roles supported by this local conformation, e.g. in the interactions between biological macromolecules. Although PPII is less frequently...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224144/ https://www.ncbi.nlm.nih.gov/pubmed/25380779 http://dx.doi.org/10.1093/database/bau102 |
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author | Chebrek, Romain Leonard, Sylvain de Brevern, Alexandre G. Gelly, Jean-Christophe |
author_facet | Chebrek, Romain Leonard, Sylvain de Brevern, Alexandre G. Gelly, Jean-Christophe |
author_sort | Chebrek, Romain |
collection | PubMed |
description | The polyproline helix type II (PPII) is a regular protein secondary structure with remarkable features. Many studies have highlighted different crucial biological roles supported by this local conformation, e.g. in the interactions between biological macromolecules. Although PPII is less frequently present than regular secondary structures such as canonical alpha helices and beta strands, it corresponds to 3–10% of residues. Up to now, PPII is not assigned by most popular assignment tools, and therefore, remains insufficiently studied. PolyprOnline database is, therefore, dedicated to PPII structure assignment and analysis to facilitate the study of PPII structure and functional roles. This database is freely accessible from www.dsimb.inserm.fr/dsimb_tools/polyproline. |
format | Online Article Text |
id | pubmed-4224144 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2014 |
publisher | Oxford University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-42241442014-11-10 PolyprOnline: polyproline helix II and secondary structure assignment database Chebrek, Romain Leonard, Sylvain de Brevern, Alexandre G. Gelly, Jean-Christophe Database (Oxford) Original Article The polyproline helix type II (PPII) is a regular protein secondary structure with remarkable features. Many studies have highlighted different crucial biological roles supported by this local conformation, e.g. in the interactions between biological macromolecules. Although PPII is less frequently present than regular secondary structures such as canonical alpha helices and beta strands, it corresponds to 3–10% of residues. Up to now, PPII is not assigned by most popular assignment tools, and therefore, remains insufficiently studied. PolyprOnline database is, therefore, dedicated to PPII structure assignment and analysis to facilitate the study of PPII structure and functional roles. This database is freely accessible from www.dsimb.inserm.fr/dsimb_tools/polyproline. Oxford University Press 2014-11-06 /pmc/articles/PMC4224144/ /pubmed/25380779 http://dx.doi.org/10.1093/database/bau102 Text en © The Author(s) 2014. Published by Oxford University Press. http://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted reuse, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Chebrek, Romain Leonard, Sylvain de Brevern, Alexandre G. Gelly, Jean-Christophe PolyprOnline: polyproline helix II and secondary structure assignment database |
title | PolyprOnline: polyproline helix II and secondary structure assignment database |
title_full | PolyprOnline: polyproline helix II and secondary structure assignment database |
title_fullStr | PolyprOnline: polyproline helix II and secondary structure assignment database |
title_full_unstemmed | PolyprOnline: polyproline helix II and secondary structure assignment database |
title_short | PolyprOnline: polyproline helix II and secondary structure assignment database |
title_sort | polypronline: polyproline helix ii and secondary structure assignment database |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224144/ https://www.ncbi.nlm.nih.gov/pubmed/25380779 http://dx.doi.org/10.1093/database/bau102 |
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