Disrupting Mitochondrial–Nuclear Coevolution Affects OXPHOS Complex I Integrity and Impacts Human Health

The mutation rate of the mitochondrial DNA (mtDNA), which is higher by an order of magnitude as compared with the nuclear genome, enforces tight mitonuclear coevolution to maintain mitochondrial activities. Interruption of such coevolution plays a role in interpopulation hybrid breakdown, speciation...

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Detalles Bibliográficos
Autores principales: Gershoni, Moran, Levin, Liron, Ovadia, Ofer, Toiw, Yasmin, Shani, Naama, Dadon, Sara, Barzilai, Nir, Bergman, Aviv, Atzmon, Gil, Wainstein, Julio, Tsur, Anat, Nijtmans, Leo, Glaser, Benjamin, Mishmar, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224335/
https://www.ncbi.nlm.nih.gov/pubmed/25245408
http://dx.doi.org/10.1093/gbe/evu208

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