The Hsp90-Dependent Proteome Is Conserved and Enriched for Hub Proteins with High Levels of Protein–Protein Connectivity

Hsp90 is one of the most abundant and conserved proteins in the cell. Reduced levels or activity of Hsp90 causes defects in many cellular processes and also reveals genetic and nongenetic variation within a population. Despite information about Hsp90 protein–protein interactions, a global view of th...

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Detalles Bibliográficos
Autores principales: Gopinath, Rajaneesh Karimpurath, You, Shu-Ting, Chien, Kun-Yi, Swamy, Krishna B.S., Yu, Jau-Song, Schuyler, Scott C., Leu, Jun-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224352/
https://www.ncbi.nlm.nih.gov/pubmed/25316598
http://dx.doi.org/10.1093/gbe/evu226

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