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Modulation of Tumorigenesis by Dietary Intervention Is Not Mediated by SIRT1 Catalytic Activity

The protein deacetylase SIRT1 is involved in the regulation of a large number of cellular processes that are thought to be required for cancer initiation and progression. Both SIRT1 activity and tumorigenesis can be influenced by dietary fat and polyphenolics. We set out to determine whether dietary...

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Detalles Bibliográficos
Autores principales: Clark-Knowles, Katherine V., Dewar-Darch, Danielle, Jardine, Karen E., McBurney, Michael W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224430/
https://www.ncbi.nlm.nih.gov/pubmed/25380034
http://dx.doi.org/10.1371/journal.pone.0112406