Poly(amidoamine) Dendrimer–Methotrexate Conjugates: The Mechanism of Interaction with Folate Binding Protein

[Image: see text] Generation 5 poly(amidoamine) (G5 PAMAM) methotrexate (MTX) conjugates employing two small molecular linkers, G5-(COG-MTX)(n), G5-(MFCO-MTX)(n) were prepared along with the conjugates of the G5-G5 (D) dimer, D-(COG-MTX)(n), D-(MFCO-MTX)(n). The monomer G5-(COG-MTX)(n) conjugates ex...

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Detalles Bibliográficos
Autores principales: van Dongen, Mallory A., Rattan, Rahul, Silpe, Justin, Dougherty, Casey, Michmerhuizen, Nicole L., Van Winkle, Margaret, Huang, Baohua, Choi, Seok Ki, Sinniah, Kumar, Orr, Bradford G., Banaszak Holl, Mark M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224518/
https://www.ncbi.nlm.nih.gov/pubmed/25222480
http://dx.doi.org/10.1021/mp500608s

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