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Astaxanthin inhibits apoptosis in alveolar epithelial cells type II in vivo and in vitro through the ROS-dependent mitochondrial signalling pathway

Oxidative stress is an important molecular mechanism underlying lung fibrosis. The mitochondrion is a major organelle for oxidative stress in cells. Therefore, blocking the mitochondrial signalling pathway may be the best therapeutic manoeuver to ameliorate lung fibrosis. Astaxanthin (AST) is an exc...

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Detalles Bibliográficos
Autores principales:	Song, Xiaodong, Wang, Bingsi, Lin, Shengcui, Jing, Lili, Mao, Cuiping, Xu, Pan, Lv, Changjun, Liu, Wen, Zuo, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224554/ https://www.ncbi.nlm.nih.gov/pubmed/25215580 http://dx.doi.org/10.1111/jcmm.12347

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