Cargando…

A novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells

The tumour suppressor activity of the phosphatase and tensin homologue on chromosome 10 (PTEN) is subject of intense investigative efforts, although limited information on its regulation in breast cancer is available. Herein, we report that, in breast cancer cells, progesterone (OHPg), through its c...

Descripción completa

Detalles Bibliográficos
Autores principales: De Amicis, Francesca, Guido, Carmela, Santoro, Marta, Lanzino, Marilena, Panza, Salvatore, Avena, Paola, Panno, Maria Luisa, Perrotta, Ida, Aquila, Saveria, Andò, Sebastiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224558/
https://www.ncbi.nlm.nih.gov/pubmed/25216078
http://dx.doi.org/10.1111/jcmm.12363