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A novel functional interplay between Progesterone Receptor-B and PTEN, via AKT, modulates autophagy in breast cancer cells
The tumour suppressor activity of the phosphatase and tensin homologue on chromosome 10 (PTEN) is subject of intense investigative efforts, although limited information on its regulation in breast cancer is available. Herein, we report that, in breast cancer cells, progesterone (OHPg), through its c...
Autores principales: | De Amicis, Francesca, Guido, Carmela, Santoro, Marta, Lanzino, Marilena, Panza, Salvatore, Avena, Paola, Panno, Maria Luisa, Perrotta, Ida, Aquila, Saveria, Andò, Sebastiano |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BlackWell Publishing Ltd
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224558/ https://www.ncbi.nlm.nih.gov/pubmed/25216078 http://dx.doi.org/10.1111/jcmm.12363 |
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