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Decreased SIRT3 in aged human mesenchymal stromal/stem cells increases cellular susceptibility to oxidative stress

Sirtuin3 (SIRT3) is an important member of the sirtuin family of protein deacetylases that is localized to mitochondria and linked to lifespan extension in organisms ranging from yeast to humans. As aged cells have less regenerative capacity and are more susceptible to oxidative stress, we investiga...

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Detalles Bibliográficos
Autores principales:	Wang, Xue-Qing, Shao, Yong, Ma, Chong-Yi, Chen, Wei, Sun, Lu, Liu, Wei, Zhang, Dong-Yang, Fu, Bi-Cheng, Liu, Kai-Yu, Jia, Zhi-Bo, Xie, Bao-Dong, Jiang, Shu-Lin, Li, Ren-Ke, Tian, Hai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2014
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224562/ https://www.ncbi.nlm.nih.gov/pubmed/25210848 http://dx.doi.org/10.1111/jcmm.12395

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