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Cenicriviroc blocks HIV entry but does not lead to redistribution of HIV into extracellular space like maraviroc
INTRODUCTION: Cenicriviroc (CVC), a once-daily, dual CCR5/CCR2 co-receptor antagonist, has completed Phase 2b development. CVC demonstrated favourable safety and similar efficacy compared with efavirenz (EFV) in Study 202 (NCT01338883); an ex vivo sub-analysis evaluated treatment effects on HIV entr...
Autores principales: | Kramer, Victor, Hassounah, Said, Colby-Germinario, Susan, Mesplède, Thibault, Lefebvre, Eric, Wainberg, Mark |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International AIDS Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224821/ https://www.ncbi.nlm.nih.gov/pubmed/25394040 http://dx.doi.org/10.7448/IAS.17.4.19531 |
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