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The effect of dolutegravir on the pharmacokinetics of metformin in healthy subjects

INTRODUCTION: Dolutegravir (DTG) is an HIV integrase strand transfer inhibitor approved for use in combination with other antiretrovirals for the treatment of HIV-infection in adults and adolescents. Metformin is a drug frequently used in diabetic HIV-infected patients, which requires titration to o...

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Detalles Bibliográficos
Autores principales: Zong, Jian, Borland, Julie, Jerva, Fred, Wynne, Brian, Choukour, Mike, Song, Ivy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4224846/
https://www.ncbi.nlm.nih.gov/pubmed/25394090
http://dx.doi.org/10.7448/IAS.17.4.19584