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Searching for an optimal AUC estimation method: a never-ending task?
An effective method of construction of a linear estimator of AUC in the finite interval, optimal in the minimax sense, is developed and demonstrated for five PK models. The models may be given as an explicit C(t) relationship or defined by differential equations. For high variability and rich sampli...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer US
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225057/ https://www.ncbi.nlm.nih.gov/pubmed/25315926 http://dx.doi.org/10.1007/s10928-014-9392-y |