MiR-630 inhibits proliferation by targeting CDC7 kinase, but maintains the apoptotic balance by targeting multiple modulators in human lung cancer A549 cells

MicroRNAome analyses have shown microRNA-630 (miR-630) to be involved in the regulation of apoptosis. However, its apoptotic role is still debated and its participation in DNA replication is unknown. Here, we demonstrate that miR-630 inhibits cell proliferation by targeting cell-cycle kinase 7 (CDC7...

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Detalles Bibliográficos
Autores principales: Cao, J-X, Lu, Y, Qi, J-J, An, G-S, Mao, Z-B, Jia, H-T, Li, S-Y, Ni, J-H
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225225/
https://www.ncbi.nlm.nih.gov/pubmed/25255219
http://dx.doi.org/10.1038/cddis.2014.386

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