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Use of dolutegravir in two INI-experienced patients with multiclass resistance resulted in excellent virological and immunological responses
INTRODUCTION: Dolutegravir is a second generation integrase inhibitor with a proposed high genetic barrier to resistance. However, in clinical trials, decreased virological response was seen in a subset of patients with prior exposure to raltegravir and multiple integrase resistance mutations. METHO...
Autores principales: | Marije Hofstra, Laura, Nijhuis, Monique, Mudrikova, Tania, Fun, Axel, Schipper, Pauline, Schneider, Margriet, Wensing, Annemarie |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International AIDS Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225339/ https://www.ncbi.nlm.nih.gov/pubmed/25397500 http://dx.doi.org/10.7448/IAS.17.4.19755 |
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