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Effect of hyperbilirubinaemia on neurocognitive, renal, bone and cardiovascular markers in HIV infection treated with boosted protease inhibitors

INTRODUCTION: Use of some protease inhibitors (PI) is associated with unconjugated hyperbilirubinaemia (HBR), due to inhibition of UGT1A1. As observed in Gilbert's syndrome, HBR may have antioxidant and anti-inflammatory effects. Inflammation may be relevant to neurocognitive (NC) impairment, c...

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Detalles Bibliográficos
Autores principales: Barber, Tristan J, Moyle, Graeme, Hill, Andrew, Jagjit Singh, Gurmit, Boffito, Marta, Nelson, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International AIDS Society 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225352/
https://www.ncbi.nlm.nih.gov/pubmed/25397571
http://dx.doi.org/10.7448/IAS.17.4.19827

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