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Accurate episomal HIV 2-LTR circles quantification using optimized DNA isolation and droplet digital PCR
INTRODUCTION: In HIV-infected patients on combination antiretroviral therapy (cART), the detection of episomal HIV 2-LTR circles is a potential marker for ongoing viral replication. Quantification of 2-LTR circles is based on quantitative PCR or more recently on digital PCR assessment, but is hamper...
Autores principales: | Malatinkova, Eva, Kiselinova, Maja, Bonczkowski, Pawel, Trypsteen, Wim, Messiaen, Peter, Vermeire, Jolien, Verhasselt, Bruno, Vervisch, Karen, Vandekerckhove, Linos, De Spiegelaere, Ward |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International AIDS Society
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225365/ https://www.ncbi.nlm.nih.gov/pubmed/25397424 http://dx.doi.org/10.7448/IAS.17.4.19674 |
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