Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia?

Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation (SpO(2)) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials. CONCLUSION: SpO(2)...

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Detalles Bibliográficos
Autores principales: Sola, Augusto, Golombek, Sergio G, Montes Bueno, María Teresa, Lemus-Varela, Lourdes, Zuluaga, Claudia, Domínguez, Fernando, Baquero, Hernando, Young Sarmiento, Alejandro E, Natta, Diego, Rodriguez Perez, Jose M, Deulofeut, Richard, Quiroga, Ana, Flores, Gabriel Lara, Morgues, Mónica, Pérez, Alfredo García-Alix, Van Overmeire, Bart, van Bel, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225465/
https://www.ncbi.nlm.nih.gov/pubmed/24838096
http://dx.doi.org/10.1111/apa.12692
Descripción
Sumario:Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation (SpO(2)) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials. CONCLUSION: SpO(2) of 85–89% can increase mortality and 91–95% can cause hyperoxia and ill effects. Neither of these ranges can be recommended, and wider intermediate targets, such as 87–94% or 88–94%, may be safer.