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Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia?
Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation (SpO(2)) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials. CONCLUSION: SpO(2)...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225465/ https://www.ncbi.nlm.nih.gov/pubmed/24838096 http://dx.doi.org/10.1111/apa.12692 |
| _version_ | 1782343513462013952 |
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| author | Sola, Augusto Golombek, Sergio G Montes Bueno, María Teresa Lemus-Varela, Lourdes Zuluaga, Claudia Domínguez, Fernando Baquero, Hernando Young Sarmiento, Alejandro E Natta, Diego Rodriguez Perez, Jose M Deulofeut, Richard Quiroga, Ana Flores, Gabriel Lara Morgues, Mónica Pérez, Alfredo García-Alix Van Overmeire, Bart van Bel, Frank |
| author_facet | Sola, Augusto Golombek, Sergio G Montes Bueno, María Teresa Lemus-Varela, Lourdes Zuluaga, Claudia Domínguez, Fernando Baquero, Hernando Young Sarmiento, Alejandro E Natta, Diego Rodriguez Perez, Jose M Deulofeut, Richard Quiroga, Ana Flores, Gabriel Lara Morgues, Mónica Pérez, Alfredo García-Alix Van Overmeire, Bart van Bel, Frank |
| author_sort | Sola, Augusto |
| collection | PubMed |
| description | Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation (SpO(2)) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials. CONCLUSION: SpO(2) of 85–89% can increase mortality and 91–95% can cause hyperoxia and ill effects. Neither of these ranges can be recommended, and wider intermediate targets, such as 87–94% or 88–94%, may be safer. |
| format | Online Article Text |
| id | pubmed-4225465 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2014 |
| publisher | Blackwell Publishing Ltd |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-42254652014-12-15 Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia? Sola, Augusto Golombek, Sergio G Montes Bueno, María Teresa Lemus-Varela, Lourdes Zuluaga, Claudia Domínguez, Fernando Baquero, Hernando Young Sarmiento, Alejandro E Natta, Diego Rodriguez Perez, Jose M Deulofeut, Richard Quiroga, Ana Flores, Gabriel Lara Morgues, Mónica Pérez, Alfredo García-Alix Van Overmeire, Bart van Bel, Frank Acta Paediatr Review Articles Oxygen is a neonatal health hazard that should be avoided in clinical practice. In this review, an international team of neonatologists and nurses assessed oxygen saturation (SpO(2)) targeting in preterm infants and evaluated the potential weaknesses of randomised clinical trials. CONCLUSION: SpO(2) of 85–89% can increase mortality and 91–95% can cause hyperoxia and ill effects. Neither of these ranges can be recommended, and wider intermediate targets, such as 87–94% or 88–94%, may be safer. Blackwell Publishing Ltd 2014-10 2014-07-28 /pmc/articles/PMC4225465/ /pubmed/24838096 http://dx.doi.org/10.1111/apa.12692 Text en © 2014 The Authors. Acta Paediatrica published by John Wiley & Sons Ltd on behalf of Foundation Acta Paediatrica. http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made. |
| spellingShingle | Review Articles Sola, Augusto Golombek, Sergio G Montes Bueno, María Teresa Lemus-Varela, Lourdes Zuluaga, Claudia Domínguez, Fernando Baquero, Hernando Young Sarmiento, Alejandro E Natta, Diego Rodriguez Perez, Jose M Deulofeut, Richard Quiroga, Ana Flores, Gabriel Lara Morgues, Mónica Pérez, Alfredo García-Alix Van Overmeire, Bart van Bel, Frank Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia? |
| title | Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia? |
| title_full | Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia? |
| title_fullStr | Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia? |
| title_full_unstemmed | Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia? |
| title_short | Safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia? |
| title_sort | safe oxygen saturation targeting and monitoring in preterm infants: can we avoid hypoxia and hyperoxia? |
| topic | Review Articles |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4225465/ https://www.ncbi.nlm.nih.gov/pubmed/24838096 http://dx.doi.org/10.1111/apa.12692 |
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